MoU Signing Ceremony on Real Estate Investments Between Cambodia and Portugal
This MoU signed is aiming to create a strategic collaboration among the four companies to mobilize fund, whilst urging real estate investments between Cambodia and Portugal, one of the European Union states.
Phnom Penh, 18 February, 2022 – Zillennium Co., Ltd (Z1 Group), Z1 Financial, Century 21 Fortuna Investment, and Canada-based Mercan Group have teamed up to create new investment opportunities in real estate to investors in Cambodia and Portugal. This collaboration will also play its vital role in attracting investors from the EU member state to inject their funds in Cambodia’s real estate sector.
These four companies have announced a strategic collaboration, singing a Memorandum of Understanding (MoU) on 18 February, 2022 at Hyatt Regency Phnom Penh. The MoU were signed by Mr. Kuy Vat, Group Chairman of Zillennium Co., Ltd, Mr. Say Sokheng, Chairman and CEO of Z1 Financial, Mr. Va Vireak, CEO of Century 21 Fortuna Investment and Mr. Jerry Morgan, President and CEO of Mercan Group.
Z1 Group is one of the leading real estate marketplaces in Cambodia. It is a local conglomerate and Singapore-based Z1 Financial – a digital asset management and investment service company – is part of its business. Century 21 Fortuna Investment is a real estate service company in Cambodia; it operates under the franchise of Century 21 Cambodia. Mercan Group is an immigration consulting company based in Canada.
Deal signed on the strategic collaboration will pave the way for these firms to work together, bringing new investment opportunities for well-off Cambodians to invest or purchase property in Portugal, and chance to obtain the country’s citizenship. Also, this partnership agreement will enable the local firms to seek and mobilize funds from investors in the EU member state to invest in Cambodia’s real estate projects.
Mr. Va Vireak, CEO of Century 21 Fortuna Investment, said Portugal is not only boasts its high potential for property investments, the country is also an attractive place to live in due to its security and modern health care system, and its living cost is relatively low in the EU bloc.
Mr. Vireak is a first Cambodian certified international property specialist (CIPS). He has an extensive experience closing property deals, especially in Portugal. The country became a member of European Union since in 1986, its population is currently standing at approximately 10 million with a gross domestic product recorded at $231 billion as of 2020.
“Property investment in Portugal is attractive. Foreigners can secure loan up to 70% of the property value, and 30% is required for down payment. Interest rate is quite interesting and relatively low at 1.2 per cent per year, with the payment term is available up to 75 years,” said Mr. Vireak, adding that “this cooperation will make it easier for Cambodian investor seeking partnership with others investors from the EU member state to invest in Cambodia’s potential sectors, especially in real estate.”
Mr. Jerry Morgan, President and CEO of Mercan Group, said this partnership will enable Cambodian investors access to profitable investment projects. According to him, 40 projects are being invested in United State, and another 15 projects in Portugal.
Jerry Morgan
CEO of Mercan Group
Comments (155)
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The Definitive Guide to Bodybuilding Supplements
(A science‑based reference for athletes, trainers, and fitness enthusiasts)
> Disclaimer: This guide is for informational purposes only.
Always consult a qualified health professional before adding new supplements to your regimen,
especially if you have medical conditions or are taking prescription medication.
—
1. Why Supplements Matter in Bodybuilding
Goal Typical Challenge How a Targeted Supplement Helps
Muscle Hypertrophy Energy deficits during high‑volume training Creatine, beta‑alanine →
↑ATP & buffer capacity
Strength Gains Limited power output Sodium bicarbonate,
creatine monohydrate → better buffering
and phosphocreatine stores
Recovery Muscle damage & inflammation Whey protein, BCAAs, omega‑3s → faster repair
& reduced soreness
Muscle Endurance Early fatigue in prolonged sessions Beta‑alanine, sodium bicarbonate → higher pH tolerance
—
4. The “Best” Supplement? How to Decide
Define Your Goal
Strength training → creatine + whey protein (or plant‑based equivalent).
Endurance sports → beta‑alanine or sodium bicarbonate for
high‑intensity intervals, plus a balanced diet.
Assess the Evidence
Prefer supplements with large, replicated RCTs that show clinically meaningful
improvements.
Look for meta‑analyses and systematic reviews.
Consider Practicality & Safety
Is it easy to dose? Does it have side effects?
For example, creatine is inexpensive, well tolerated
(except for rare gastrointestinal upset), and has minimal risk when taken at recommended doses (~5 g/day).
Integrate Into Your Routine
Supplements should augment—not replace—nutrition and training.
Use a periodized approach: test the supplement in a “block” of weeks, monitor
response, then decide whether to continue.
—
Quick Decision Matrix (Simplified)
Goal Likely Best Supplement Practical Notes
Maximize strength & power Creatine monohydrate 5 g/day;
low cost; high evidence.
Increase lean muscle mass (hypertrophy) Protein supplement (whey or plant-based) + creatine Combine for optimal anabolic environment.
Improve recovery after intense workouts BCAAs/EAAs, glutamine Mixed evidence; consider whole protein instead.
Enhance endurance performance Beetroot juice / nitrate tablets 5–7 mL beetroot concentrate daily
before event.
Reduce soreness & inflammation Omega‑3 fatty acids
(EPA/DHA) 1–2 g/day EPA+DHA; anti-inflammatory effect.
—
How to Choose Wisely
Question Answer Recommendation
What is my main goal? Strength, endurance, recovery, or general health Pick the supplement that directly supports that goal
Do I need a supplement? Can I meet needs through diet?
Prioritize whole foods; supplements fill
gaps only
Is it safe? FDA‑regulated? Look for third‑party testing (USP, NSF)
and avoid products with unverified claims
Will it interact with meds or conditions? e.g., St. John’s wort &
antidepressants Consult your doctor before starting
Am I overdoing it? Multiple high‑dose supplements Avoid excessive intake; follow recommended doses
—
5. Quick Reference Tables
A. Popular Supplements & Typical Doses (if you decide to
use them)
Supplement Common Dose Key Benefits Caution / Note
Vitamin D₃ 1,000–2,000 IU daily (or per doctor) Bone health, immune support Watch for hypercalcemia with high
doses.
Omega‑3 (EPA/DHA) 250–500 mg EPA + DHA/day Heart & brain health
Blood thinning at >1 g/day.
Vitamin B₁₂ 200–2,000 µg daily Energy, nerve
function Usually safe; excess excreted.
Folate (folic acid) 400 µg daily Pregnancy & red‑blood cell production Excess may mask B₁₂ deficiency.
Calcium 1,000–1,200 mg/day Bone health Over‑supplementation may cause constipation or kidney
stones.
> Key takeaway: If your diet is balanced and you meet the recommended daily allowances (RDAs) for
these nutrients, supplements are usually unnecessary. Supplements should be
used when a specific deficiency is diagnosed or for high-risk groups (e.g.,
pregnant women need folic acid; older adults may benefit from vitamin D).
—
2. When supplements might be useful
Situation Why it’s beneficial Typical supplement
Pregnancy Folic acid reduces neural‑tube defects, iron supports fetal growth.
Prenatal multivitamin (with folic acid, iron, iodine).
Older adults Vitamin D deficiency common due to reduced skin synthesis
and dietary intake; may aid bone health. 800–2000 IU vitamin D₃ daily.
Vegetarians/vegans Limited B12 sources in plant
foods. 250–500 µg methylcobalamin or cyanocobalamin daily.
Low sunlight exposure Inadequate UV‑B can lead to low vitamin D.
Vitamin D supplement as above, especially in winter.
Pregnancy & lactation Increased needs for folate and iron; some may require prenatal vitamins.
Prenatal vitamin with 400 µg folic acid, 30–60 mg iron.
> Tip: Use a high‑quality multivitamin to cover the bases, but focus on specific nutrients that your diet lacks.
—
3. The Role of Vitamin D in Bone Health
Vitamin D is essential for calcium absorption and bone mineralization. Inadequate vitamin D leads to:
Reduced calcium uptake → lower bone density
Compensatory increase in parathyroid hormone (PTH) → bone resorption
Recommended intake:
Age Group RDA (IU/day) Notes
19‑50 yr 600 Adequate for most adults with moderate sun exposure
>51 yr 800–1000 Higher due to reduced skin synthesis and absorption
Sunlight: 10–30 min of midday sun on arms/legs, several
times per week. For darker skin or winter months, supplements may be necessary.
—
2. Calcium – the main mineral for bone density
Optimal daily intake
Age Group RDA (mg/day)
Adults 19‑50 yr 1 000
Adults >51 yr 1 200
Sources
– Dairy: milk, cheese, yogurt.
– Fortified plant milks (soy, almond).
– Leafy greens (kale, collard greens).
– Fish with edible bones (canned sardines).
– Calcium‑fortified orange juice.
Calcium‑supplement strategy
Preferred intake: Get most calcium from food. Supplements are useful if dietary
intake is insufficient.
Dosage: If supplementing, aim for ≤500 mg per dose to
maximize absorption (the body absorbs ~30–40% of
a 200‑mg dose).
Timing: Take calcium supplements with meals or a snack; avoid taking them simultaneously with iron, magnesium, zinc, or large doses of vitamin C, as these can interfere with absorption.
Avoid high‑dose single servings: Taking >500 mg in one go is less effective than splitting into two smaller
doses (e.g., 250 mg twice daily).
3. Vitamin D – How Much and Why?
Goal Suggested Daily Dose
General health / bone maintenance 600–800 IU/day (1500–2000 IU for older adults or those with limited sun exposure)
Deficiency correction 10 000 IU/week (~1 428 IU/day) for several weeks,
then taper to maintenance dose
High‑risk groups (older adults, dark skin, obesity,
chronic disease) 2 000–4 000 IU/day, or a loading dose of 50 000 IU once per month
Rationale: Vitamin D is essential for calcium absorption and bone health.
It also modulates immune function—higher levels are associated with reduced risk
of respiratory infections, including COVID‑19.
Safety: Toxicity rarely occurs at doses up to 10 000 IU/day; however,
monitor serum 25(OH)D in patients taking >4 000 IU/day or those with chronic kidney
disease.
3. Vitamin C (Ascorbic Acid)
Suggested Intake Timing & Form Notes
Adults: 500 mg–2 g per day Oral tablets or capsules; divided doses to improve absorption. Consider a high‑dose 1‑hour
infusion (e.g., 10 mmol/kg) in severe infection. Antioxidant, supports immune cell function, reduces oxidative stress.
During acute infection 1–2 g every 8 h orally or IV if oral intake inadequate.
Clinical trials suggest benefit when given early; high doses may be required for
immunomodulatory effects.
Safety: Generally safe up to 4 g/day orally.
High doses may cause GI upset or hypoglycemia in some individuals.
5. Zinc Supplementation
Rationale: Zinc is essential for innate and adaptive immunity, including T‑cell maturation.
It also has antiviral activity by inhibiting viral replication enzymes.
Dosage: 20–40 mg elemental zinc (as zinc acetate or gluconate) once daily.
Timing: Start as soon as possible after symptom onset.
Safety: Keep total daily intake ≤45 mg to avoid copper deficiency and gastrointestinal side effects.
Avoid high‑dose (>50 mg) for prolonged periods.
6. Omega‑3 Fatty Acids (EPA/DHA)
Rationale: EPA and DHA have anti‑inflammatory properties,
modulating cytokine production and supporting immune regulation.
Dosage: 1–2 g/day of combined EPA+DHA.
Timing: Start early in the illness; continue for at
least 10 days.
Safety: Generally well tolerated. Monitor bleeding risk
if on anticoagulants.
7. Probiotic Supplementation
Rationale: Certain probiotic strains (e.g., Lactobacillus rhamnosus GG,
Bifidobacterium lactis) can enhance mucosal immunity and reduce viral
replication in the gut.
Dosage: As per product label, typically 1–10 CFU billions/day.
Timing: Initiate at illness onset; continue for 7–14 days post-recovery.
Safety: Low risk; monitor for mild GI disturbances.
8. Zinc Supplementation
Rationale: Zinc is essential for antiviral immunity and
may inhibit viral replication of RNA viruses, including coronaviruses.
Dosage: 15 mg elemental zinc/day (as zinc gluconate or
sulfate).
Timing: Begin at symptom onset; continue until recovery.
Safety: Monitor for nausea; high doses (>50 mg/day) can cause GI upset and interfere with
copper absorption.
9. Antioxidant Vitamins (Vitamin C, Vitamin E)
Rationale: Oxidative stress is a component of viral pathogenesis; antioxidants may mitigate
damage.
Dosage:
– Vitamin C: 500–1000 mg/day.
– Vitamin E: 400 IU/day (α-tocopherol).
Timing: Start at diagnosis and continue until resolution.
10. Probiotics
Rationale: Support gut microbiota, potentially modulating
immune response.
Dosage: Commercially available strains (e.g., Lactobacillus rhamnosus GG) with ≥10⁹ CFU per dose, taken once daily for
2–4 weeks.
IV. Monitoring Protocol
Parameter Frequency Target/Alert
Temperature Twice daily (morning & evening)
>38.5 °C → evaluate for fever source; consider antipyretic
Heart Rate / BP Daily Tachycardia >120 bpm or hypotension 2% change
→ reassess fluid balance
Laboratory Values: CBC, electrolytes, BUN/Creatinine, glucose, lactate At baseline; repeat if clinically indicated
(e.g., signs of sepsis) Elevated values → investigate source
4.3 Decision Points
Fluid Resuscitation Threshold: If urine output 1 mL/kg/h), advance diet gradually.
Discharge Criteria: Normal vital signs for ≥12 h, tolerating full oral
intake, adequate hydration (≥2 mL/kg/h urine output), no abdominal pain or vomiting.
4. Patient‑Friendly Guide to Managing Fever and Diarrhoea in Children
Understanding the Problem
Fever is your child’s way of fighting infection.
Diarrhoea can happen when bacteria, viruses, or parasites upset the gut.
The two together often mean a viral illness (e.g., rotavirus) or bacterial
infection.
Quick Actions at Home
Symptom What to Do
Fever > 38.5 °C Give paracetamol/ibuprofen as per dose chart.
Re‑check temperature after 30 min; repeat if still high.
Diarrhoea (≥ 3 loose stools in 24 h) Offer oral rehydration solution (ORS) or homemade
mixture (1 L clean water + 6 tsp sugar + ½ tsp salt).
Give small sips frequently.
Vomiting Keep child hydrated with ORS or clear fluids; avoid solid food until vomiting
stops.
Signs of dehydration (dry mouth, decreased tears, lethargy)
Seek urgent medical care; start IV fluids if
needed.
—
2. Home‑Based Management Plan
Condition Immediate Action Ongoing Care When to Escalate
Acute Dehydration (vomiting, diarrhea) Start oral rehydration; add electrolyte solution.
Monitor weight and urine output; continue ORS until normal intake resumes.
Severe lethargy, seizures, rapid heart rate.
Diarrhea (non‑bloody) Encourage fluids; give zinc 10 mg daily for 10 days.
Keep a stool diary; avoid heavy fats or sugary drinks.
Blood in stool, persistent fever >38.5°C for >48h.
Vomiting Give antiemetic only if needed; monitor hydration. Avoid giving solids until vomiting stops.
Vomiting lasting >24 hrs, dehydration signs.
Fever Use paracetamol 15 mg/kg every 6–8 hr
as needed. Monitor temperature trend. Temperature >38.5°C for >48h or chills.
—
4. Follow‑up & Monitoring
Item Frequency Notes
Telehealth check (phone/WhatsApp) Day 3 post‑admission and day 7 if
still symptomatic Ask about fever, breathing, cough,
GI symptoms.
In‑person visit Day 10–14 after discharge or earlier if any new/worsening
symptom Full vitals, pulse oximetry; review
labs if indicated.
Pulse Oximeter use at home Daily Record readings; seek medical
advice if SpO₂ 3% from baseline.
Follow‑up chest X‑ray If persistent cough/dyspnea after
4–6 weeks Assess for fibrosis, atelectasis.
Mental health screening At first follow‑up visit Screen for anxiety, depression;
refer to counseling if needed.
—
8. Practical Recommendations for the Family
Continue regular monitoring of body temperature and oxygen saturation (using a validated home pulse oximeter).
Maintain good hydration and balanced nutrition—small frequent meals may be easier
after illness.
Encourage rest: allow sufficient sleep; avoid over‑exertion in the first weeks.
Engage in gentle, progressive physical activity: e.g., walking or light stretching, once no fatigue or cough is present.
Avoid exposure to smoking or pollutants—air quality
can affect respiratory recovery.
Stay connected with healthcare providers: report any new symptoms (e.g., shortness of breath, chest pain, fever) promptly.
4. Key Take‑Home Points for the Family
Topic What It Means for Your Daughter How to Support
Pulmonary Function Test (PFT) Shows reduced airflow and capacity – signs of airway narrowing or lung restriction. Monitor symptoms; encourage adherence to inhaler/medication if prescribed.
Spirometry Indicates that her lungs are not fully open‑ing, but still within normal limits for
a child. Keep track of any cough or wheeze after exercise; report changes early.
Diffusing Capacity (DLCO) Normal – suggests no problem with gas exchange in the lung tissue itself.
No specific action needed unless new symptoms appear.
Transfer Factor (TLCO) Slightly low, but still within acceptable range for her age.
Keep an eye on exercise tolerance; ensure adequate rest and hydration.
—
4️⃣ Key Take‑Aways
Overall: The child’s lung function is good with no major concerns.
Potential Concern: Mild reduction in DLCO/TLCO may hint at
a small amount of inflammation or scarring, but it is not clinically significant yet.
Monitoring: Recheck in 6–12 months if symptoms
(cough, shortness of breath) develop or persist.
Lifestyle: Encourage regular physical activity and avoid exposure to smoke or pollutants.
📚 Quick Glossary
Term What It Means
FEV1/FVC Ratio How fast you can blow out air compared to the total amount you can exhale.
DLCO How well oxygen moves from your lungs into
your blood.
Kleiber’s Law A rule that helps scientists predict how body size relates to metabolism and organ function.
—
💬 Got questions? Drop them in the comments or DM me!
Let’s keep our lungs healthy together. 🌟
ealth #PulmonaryFunction #KleibersLaw #LungHealth #MedicalScience #Physiology #StayHealthy
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that a well-defined study set for Klebsiella pneumoniae
(a single)
We need to research my case study on it.
We are explain the case study?
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The case study
Title
Sure, here’s a concise outline for your Klebsiella pneumoniae case study:
—
Case Study Title:
Revised Case Study – Disconnected Diagnosis and Treatment of Klebsiella pneumoniae Infection
—
1. Introduction
Brief overview of Klebsiella pneumoniae (Kp)
Importance in clinical settings
2. Patient Profile
Age, gender, relevant medical history
Initial presentation symptoms
3. Clinical Findings
Physical examination results
Laboratory test results (blood cultures, imaging)
4. Diagnosis
Confirmation of Kp infection
Identification different mgs of
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5. Treatment Plan
Initial empiric therapy
Adjustments based on sensitivity data
6. Outcome and Follow-up
Patient’s response to treatment
Any complications or relapses
Summary
Klevelia pra‑eticia is a gram‑negative, facultative anaerobe that thrives in moist environments such as
irrigation systems and can cause opportunistic infections, particularly in immunocompromised
hosts. It is intrinsically resistant to many β‑lactam antibiotics due to the production of
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additional resistance mechanisms (extended‑spectrum
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and propensity for nosocomial transmission make it a relevant pathogen in healthcare settings.
Understanding its microbiological traits, clinical spectrum, resistance mechanisms, infection control implications, and therapeutic options is essential for accurate diagnosis, effective treatment, and prevention of outbreaks.
—
Key Points
A. baumannii is intrinsically resistant to many β‑lactams
due to chromosomal β‑lactamases; it readily acquires additional
resistance determinants.
The bacterium thrives in dry, nutrient‑poor
environments such as hospital surfaces and irrigation systems, forming protective biofilms.
Nosocomial infections can be severe, especially in immunocompromised or
ICU patients, with high mortality rates when multidrug‑resistant strains are
involved.
Infections linked to contaminated water sources underscore the need for stringent disinfection protocols and monitoring of environmental reservoirs.
Treatment options are limited; colistin remains a key agent, but resistance is emerging, necessitating novel
therapeutic strategies.
This synthesis highlights how environmental resilience and adaptive resistance mechanisms
contribute to the persistence and spread of Klebsiella pneumoniae* in healthcare settings.
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